Monsuno hurtled through space eons before man existed. Upon burning through the planet's atmosphere and crashing to Earth, it brought chaos and the extinction of the dinosaurs. Then, it vanished. Now, Monsuno is back. Is the Earth doomed?
Team Core Tech faces off against Drezz and the Punk Monks, members of the Forge Resistance that work for the evil Professor Tallis in their attempts to obtain a very destructive Wild Core Bomb with enough power to level an entire city.
Team Core Tech must prevent the Forge Resistance from executing their plan to destroy Westward City with a Mega Wild Core Bomb. After intense fighting, Bren launches Neo-Quickforce, while Chase attempts to jettison the bomb into space.
Medea and Team Darkspin follow Team Core Tech, as Medea has a secret new Benefactor. Meanwhile, Team Core Tech is out looking for meteor fragments and data on Monsuno Essence for Dr. Jeredy Suno's world-saving work.
On the trail of a big cache of Monsuno Essence, our heroes walk into a trap set by S.T.O.R.M.'s Strike Squad, a new group of Monsuno controllers made up of juvenile delinquents handpicked by Charlemagne and Commander Trey.
Dr. Klipse has an old score to settle with Dax, so he hires Dom Pyro to capture him, but Dax does not go down without a fight. When Dax is captured and placed into a tank where he will be experimented on, Team Core Tech arrives.
Dr. Klipse's latest experiment is a teenage clone of himself he has named Number 6. Upon sending the clone out into the world to destroy Team Core Tech, Chase and the others discover Number 6 and mistakenly invite him to join them.
After waking up in a strange, apocalyptic land, Chase finds himself in a battle with a clone Monsuno. When Chase is absorbed by a horrible shadow-ghost, he becomes the enemy, leaving the rest of Team Core Tech to face a deep mystery.
When Jeredy Suno reveals the mystery of Lock as the lynchpin that bridges humanity and all Monsunos, Dr. Klipse and his cloned son, Number 6, work with Don Pyro to attempt to steal Lock, and destroy Chase.
While tracking down Drezz, the Punk Monks, and their Forge Cores, the Monsuno 5 are attacked by mysterious figures representing The Hand of Destiny, composed of five evil despots who seek to capture and imprison Chase to steal his energy.
Jeredy discovers that S.T.O.R.M. is stockpiling Monsuno Essence and sends Team Core-Tech to secure it. However, One-Eyed Jack and the Desert Wolves get there first and plan to turn all the Essence into a bomb that decimate the continent.