Peter Silver is a young doctor treading water in the wake of a breakup-his ex–girlfriend called him a ""mama's boy"" and his best friend considers him a ""homebody,"" a squanderer of adventure. But when he receives an unexpected request for a house call, he obliges, only to discover that his new patient is aging, chameleonic rock star Jimmy Cross. Soon Peter is compelled to join the mysteriously ailing celebrity, his band, and his entourage, on the road. The so–called ""first physician embedded in a rock tour,"" Peter is thrust into a way of life that embraces disorder and risk rather than order and discipline.
