Sarah is out of options, on the run, and pursued by deadly adversaries. Desperate to find her daughter Kira, Sarah suspects ruthless pro-clone Rachel is behind her daughter's disappearance and sparks an all out war against her. Alison and Donnie attend the funeral of her fallen friend, Aynsley, causing Alison to sink into guilt and despair. Cosima is faced with a perplexing decision that may have dire consequences.
While Alison struggles with Aynsley's death and Cosima grapples with the worsening symptoms of her mysterious sickness, Sarah enlists Art's help to find Kira and is shocked when she learns where the trail leads.
After hitting the road with Felix, Sarah is forced to turn to a ghost from her past - an old flame named, Cal Morison. When their brief respite is brutally shattered, Sarah realizes that no matter how far she runs, it will never be far enough.
Sarah comes home to look for answers. With Cosima's help, she digs into the origins of the clone experiment. The hunt takes her right into the belly of the beast, but getting out again could cost her more than she knows.
Rachel goes on the warpath, lashing out at Sarah's nearest and dearest. While she tries to keep her loved ones safe, an unexpected visitor threatens to derail Sarah's plans.
Sarah joins forces with an unlikely - and untrustworthy - ally, following a trail of clues that she hopes will lead her to the origins of the clone experiment. Cosima and Delphine make a discovery that could prove the key to treating her illness. Alison finds herself in unsavory company at rehab.
