MALDI-TOF and Tandem MS for Clinical Microbiology

This book highlights the triumph of MALDI-TOF mass spectrometry over the past decade and provides insight into new and expanding technologies through a comprehensive range of short chapters that enable the reader to gauge their current status and how they may progress over the next decade. This book serves as a platform to consolidate current strengths of the technology and highlight new frontiers in tandem MS/MS that are likely to eventually supersede MALDI-TOF MS. Chapters discuss:

Challenges of Identifying Mycobacterium to the Species level

Identification of Bacteroides and Other Clinically Relevant Anaerobes

Identification of Species in Mixed Microbial Populations

Detection of Resistance Mechanisms

Proteomics as a biomarker discovery and validation platform

Determination of Antimicrobial Resistance using Tandem Mass Spectrometry